Thermodynamic protonation constant values of meclizine and buclizine in acetonitrile-water binary mixtures
نویسندگان
چکیده
منابع مشابه
Determination of Protonation Constants of Some Tetracycline Antibiotics by Potentiometry and LC Methods in Water and Acetonitrile-Water Binary Mixtures
Uma estimativa acurada das constantes de dissociação de antibióticos tetraciclina em misturas binárias acetonitrila-água é muito importante para muitas técnicas de separação, como cromatografia líquida e eletroforese capilar que usam essas misturas de solvente. Neste estudo, os valores de pK a de cinco tetraciclinas (tetraciclina, oxitetraciclina, clorotetraciclina, doxiciclina e metaciclina) f...
متن کاملInfluence of dielectric constant on protonation equilibria of L-aspartic Acid in acetonitrile- and ethylene glycol-water mixtures.
The protonation constants of L-Aspartic acid have been studied pH-metrically in various concentrations (0-60% v/v) of acetonitrile- and ethylene glycol-water mixtures maintaining an ionic strength of 0.16 mol L-1 at 303K. The protonation constants have been calculated with the computer program MINIQUAD75 and are selected based on statistical parameters. Linear variation of step-wise protonation...
متن کاملDetermination of pKa Values of Some Sulfonamides by LC and LC-PDA Methods in Acetonitrile-Water Binary Mixtures
As constantes de dissociação de sete sulfonamidas antibióticas, sulfadiazina, sulfatiazol, sulfamerazina, sulfametazina, sulfamonometoxina, sulfadoxina e sulfametoxazol, foram determinadas em diferentes misturas binárias acetonitrila-água (15, 30, 40, 50% (v/v)) usando cromatografia líquida de fase reversa. Um método usando espectros de absorbância no máximo dos picos cromatográficos previament...
متن کاملEvaluation of methanol-water and acetonitrile-water binary mixtures as eluents for temperature-dependent inclusion chromatography.
In the present study the solubility of beta-cyclodextrin and 2-hydroxypropyl-beta-cyclodextrin at sub-zero and elevated temperatures (-10 and +30 degrees C) for a given composition of methanol/water and acetonitrile/water binary mixtures (Xs = 0.16) was studied. Moreover, the freezing temperature profiles of acetonitrile-based chromatographic mobile phases were measured, and the obtained result...
متن کاملA Thermodynamic Study of Complex Formation between 15-Crown-5 with Mg2+, Ca2+, Sr2+ and Ba2+ in Acetonitrile Methanol Binary Mixtures Using Conductometric Method
The complexation reactions between Mg2+, Ca2+, Sr2+ and Ba2+ metal cations with 15-crown-5 (15C5) were studied in acetonitrile (AN)-methanol (MeOH) binary mixtures at different temperatures using conductometric method. 15C54 forms 1:1 complexes with Mg2+, Ca2+ and Sr2+ cations in solutions. The Ma2+ cati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Research in Pharmacy
سال: 2021
ISSN: 2630-6344
DOI: 10.35333/jrp.2021.290